Jennifer L. Meagher - Concepedia

Concepedia

Author

Jennifer L. Meagher

University of Michigan ORCID

Also Known As

J. Meagher, J.L. Meagher, Jennifer L Meagher, Jennifer L. Meagher, Jennifer Meagher, Jennifer L. Meagher, Schols, Dominique

116

Publications

4.6K

Citations

37

H-Index

74

Concepts

All Affiliations

University of Michigan National Cancer Institute University of Illinois Chicago National Institutes of Health Michigan Center for Translational Pathology

JL

About

Jennifer L. Meagher is an author at University of Michigan specializing in medicine, molecular biology, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	22	25	2.7K
2	Natural Sciences	16	17	1.6K
3	Biochemistry	14	14	1.2K
4	Biomolecular Engineering	3	3	226
5	Engineering	2	2	64

Jennifer L. Meagher

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53

Publications

4.6K

Citations

37

H-Index

	Year	Citations
A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo Longchuan Bai, Haibin Zhou, Renqi Xu, Cancer Cell Cancer ResearchMedicineSmall MoleculesSelective Small-molecule DegraderTumor Targeting	2019	575
SAR405838: An Optimized Inhibitor of MDM2–p53 Interaction That Induces Complete and Durable Tumor Regression Shaomeng Wang, Wei Sun, Yujun Zhao, Cancer Research	2014	335
Structure-Based Design of Potent Small-Molecule Inhibitors of Anti-Apoptotic Bcl-2 Proteins Guoping Wang, Zaneta Nikolovska‐Coleska, Chao‐Yie Yang, Journal of Medicinal Chemistry	2006	293
Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression Chong Qin, Yang Hu, Bing Zhou, Journal of Medicinal Chemistry Molecular BiologyBet ProteinsBet InhibitorsTumor BiologyMedicinal Chemistry	2018	258
Structure-Based Discovery of SD-36 as a Potent, Selective, and Efficacious PROTAC Degrader of STAT3 Protein Haibin Zhou, Longchuan Bai, Renqi Xu, Journal of Medicinal Chemistry Stat3 Sh2 DomainProtein AssemblyMolecular BiologyCancer BiologyTumor Biology	2019	201
Design, Synthesis, and Characterization of a Potent, Nonpeptide, Cell-Permeable, Bivalent Smac Mimetic That Concurrently Targets Both the BIR2 and BIR3 Domains in XIAP Haiying Sun, Zaneta Nikolovska‐Coleska, Jianfeng Lü, Journal of the American Chemical Society	2007	200
SM-164: A Novel, Bivalent Smac Mimetic That Induces Apoptosis and Tumor Regression by Concurrent Removal of the Blockade of cIAP-1/2 and XIAP Jianfeng Lü, Longchuan Bai, Haiying Sun, Cancer Research Tumor RegressionApoptosis ProteinApoptosisImmunologyCell Death	2008	200
Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer Longchuan Bai, Bing Zhou, Chao‐Yie Yang, Cancer Research	2017	198
Structure of the zinc-finger antiviral protein in complex with RNA reveals a mechanism for selective targeting of CG-rich viral sequences Jennifer L. Meagher, Matthew A. Takata, Daniel Gonçalves-Carneiro, Proceedings of the National Academy of Sciences Crystal StructureViral ReplicationMolecular BiologySelective TargetingViral Structural Protein	2019	147
Crystal structure of banana lectin reveals a novel second sugar binding site Jennifer L. Meagher, Harry C. Winter, P. Ezell, Glycobiology Crystal StructureBiochemistryFamily MembersProtein FoldingMedicine	2005	123

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