Junko Sone

2′-O,4′-C-ethylene-bridged nucleic acids (ENA): highly nuclease-resistant and thermodynamically stable oligonucleotides for antisense drug

Koji Morita, Chikako Hasegawa, Masakatsu Kaneko et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 184 citations

Pharmacy, Biochemistry, Molecular Biology +15

Synthesis and properties of 2′-O,4′-C-Ethylene-Bridged nucleic acids (ENA) as effective antisense oligonucleotides

Koji Morita, Miho Takagi, Chikako Hasegawa et al. · Bioorganic & Medicinal Chemistry · 2003 · 131 citations

Pharmacy, Chemistry, Molecular Biology +14

Biologically Active Oligodeoxyribonucleotides. 5. 5‘-End-Substituted d(TGGGAG) Possesses Anti-Human Immunodeficiency Virus Type 1 Activity by Forming a G-Quadruplex Structure

Hitoshi Hotoda, Makoto Koizumi, Rika Koga et al. · Journal of Medicinal Chemistry · 1998 · 91 citations

Life Sciences, Biochemistry, Pharmacology +17

Biologically active oligodeoxyribonucleotides—IX.1 Synthesis and anti-HIV-1 activity of hexadeoxyribonucleotides, TGGGAG, bearing 3′- and 5′-end-modification

Makoto Koizumi, Rika Koga, Hitoshi Hotoda et al. · Bioorganic & Medicinal Chemistry · 1997 · 41 citations

Life Sciences, Biochemistry, Molecular Biology +15

Biologically active oligodeoxyribonucleotides. Part 12:1 N2-Methylation of 2′-deoxyguanosines enhances stability of parallel G-quadruplex and anti-HIV-1 activity

Makoto Koizumi, Keika Akahori, Toshinori Ohmine et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 25 citations

Life Sciences, Biochemistry, Molecular Biology +16