Miho Takagi

Synthesis and properties of 2′-O,4′-C-Ethylene-Bridged nucleic acids (ENA) as effective antisense oligonucleotides

Koji Morita, Miho Takagi, Chikako Hasegawa et al. · Bioorganic & Medicinal Chemistry · 2003 · 131 citations

Pharmacy, Chemistry, Molecular Biology +14

Chimeric RNA/Ethylene-Bridged Nucleic Acids Promote Dystrophin Expression in Myocytes of Duchenne Muscular Dystrophy by Inducing Skipping of the Nonsense Mutation-Encoding Exon

Agus Surono, Trần Vân Khánh, Yasuhiro Takeshima et al. · Human Gene Therapy · 2004 · 55 citations

Life Sciences, Genetics, Molecular Biology +15

Chimeric RNA and 2′- <i>O</i> , 4′- <i>C</i> -Ethylene-Bridged Nucleic Acids Have Stronger Activity Than Phosphorothioate Oligodeoxynucleotides in Induction of Exon 19 Skipping in Dystrophin mRNA

Mariko Yagi, Yasuhiro Takeshima, Agus Surono et al. · Oligonucleotides · 2004 · 34 citations

Life Sciences, Genetics, Molecular Biology +12

Enhancement of the Inhibitory Activity of oatp Antisense Oligonucleotides by Incorporation of 2‘-<i>O</i>,4‘-<i>C</i>-Ethylene-Bridged Nucleic Acids (ENA) without a Loss of Subtype Selectivity

Miho Takagi, Koji Morita, Daisuke Nakai et al. · Biochemistry · 2004 · 18 citations

Pharmacy, Biotechnology, Molecular Biology +17

Truncated UDP-glucuronosyltransferase (UGT) from a Crigler–Najjar syndrome type II patient colocalizes with intact UGT in the endoplasmic reticulum

Masahiro Suzuki, Marie Hirata, Miho Takagi et al. · Journal of Human Genetics · 2014 · 12 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10