Rika Koga

Biologically Active Oligodeoxyribonucleotides. 5. 5‘-End-Substituted d(TGGGAG) Possesses Anti-Human Immunodeficiency Virus Type 1 Activity by Forming a G-Quadruplex Structure

Hitoshi Hotoda, Makoto Koizumi, Rika Koga et al. · Journal of Medicinal Chemistry · 1998 · 91 citations

Life Sciences, Biochemistry, Pharmacology +17

Biologically active oligodeoxyribonucleotides—IX.1 Synthesis and anti-HIV-1 activity of hexadeoxyribonucleotides, TGGGAG, bearing 3′- and 5′-end-modification

Makoto Koizumi, Rika Koga, Hitoshi Hotoda et al. · Bioorganic & Medicinal Chemistry · 1997 · 41 citations

Life Sciences, Biochemistry, Molecular Biology +15

Biologically active oligodeoxyribonucleotides. Part 11: The least phosphate-modification of quadruplex-forming hexadeoxyribonucleotide TGGGAG, bearing 3′- and 5′-end-modification, with anti-HIV-1 activity

Makoto Koizumi, Rika Koga, Hitoshi Hotoda et al. · Bioorganic & Medicinal Chemistry · 1998 · 22 citations

Life Sciences, Biochemistry, Molecular Biology +16

Biologically Active Oligodeoxyribonucleotides - IV: Anti-HIV-1 Activity of Tgggag Having Hydrophobic Substituent at Its 5′-End via Phosphodiester Linkage

Hitoshi Hotoda, Makoto Koizumi, Rika Koga et al. · Nucleosides and Nucleotides · 1996 · 16 citations

Life Sciences, Biochemistry, Molecular Biology +10

Protection of hu-PBL-SCID/beige mice from HIV-1 infection by a 6-mer modified oligonucleotide, R-95288

Toshinori Agatsuma, Kohji Abe, Hidehiko Furukawa et al. · Antiviral Research · 1997 · 11 citations

Life Sciences, Immunology, Infectious Diseases +10