Biologically active oligodeoxyribonucleotides. Part 11: The least phosphate-modification of quadruplex-forming hexadeoxyribonucleotide TGGGAG, bearing 3′- and 5′-end-modification, with anti-HIV-1 activity

References

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	Year	Citations
Cholesteryl-conjugated oligonucleotides: synthesis, properties, and activity as inhibitors of replication of human immunodeficiency virus in cell culture. Robert L. Letsinger, G R Zhang, Di Sun, Proceedings of the National Academy of Sciences Molecular BiologyCell CultureAntiviral DrugHuman Immunodeficiency VirusChemical Biology	1989	302
Combinatorially selected guanosine-quartet structureis a potent inhibitor of human immunodeficiency virus envelope-mediated cellfusion. Jacqueline R. Wyatt, Timothy A. Vickers, Joseph L. Roberson, Proceedings of the National Academy of Sciences Potent InhibitorTetramer FormationImmunologyMolecular BiologyGuanosine-quartet Structureis	1994	300
Complement Activation and Hemodynamic Changes Following Intravenous Administration of Phosphorothioate Oligonucleotides in the Monkey W M Galbraith, W. Hobson, Patricia C. Giclas, Antisense Research and Development ImmunologyBlood CellGem 91Rapid Intravenous InfusionPhosphorothioate Oligonucleotides	1994	237
Internucleotide phosphite sulfurization with tetraethylthiuram disulfide. Phosphorothioate oligonucleotide synthesis via phosphoramidite chemistry Huynh Vu, Bernard L. Hirschbein Tetrahedron Letters BiosynthesisBioorganic ChemistryPhosphoramidite ChemistryBiochemistryEngineering	1991	148
Suppression of Human Immunodeficiency Virus Type 1 Activity in Vitro by Oligonucleotides Which Form Intramolecular Tetrads Robert F. Rando, Joshua O. Ojwang, Ahmed Elbaggari, Journal of Biological Chemistry	1995	120
T30177, an oligonucleotide stabilized by an intramolecular guanosine octet, is a potent inhibitor of laboratory strains and clinical isolates of human immunodeficiency virus type 1 J O Ojwang, Robert W. Buckheit, Yves Pommier, Antimicrobial Agents and Chemotherapy Hiv-1 IntegrasePotent InhibitorImmunologyMolecular BiologyT30177 Inhibited Replication	1995	104
Inhibition of High Affinity Basic Fibroblast Growth Factor Binding by Oligonucleotides Susan M. Fennewald, Robert F. Rando Journal of Biological Chemistry Human GrowthMolecular BiologyCytoskeletonCell GrowthCellular Physiology	1995	85
Mode of action of 5'-linked cholesteryl phosphorothioate oligodeoxynucleotides in inhibiting syncytia formation and infection by HIV-1 and HIV-2 in vitro Christian Stein, Ranajit Pal, Anthony L. DeVico, Biochemistry	1991	83
Deprotection of methylphosphonate oligonucleotides using a novel one-pot procedure Richard I. Hogrefe, Morteza M. Vaghefi, Mark A. Reynolds, Nucleic Acids Research Medicinal ChemistryBioorganic ChemistryAldehyde DehydrogenaseBiochemistryNatural Sciences	1993	81
Phosphorothioate Oligodeoxynucleotides Bind to the Third Variable Loop Domain (v3) of Human Immunodeficiency Virus Type 1 gp120 Christian Stein, Aileen M. Cleary, L. A. Yakubov, Antisense Research and Development	1993	81

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