Roos L. Oostendorp

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis

Laura J. Niedernhofer, George A. Garinis, Anja Raams et al. · Nature · 2006 · 661 citations

Medicine, Endocrinology, Pathology +11

The effect of P-gp (Mdr1a/1b), BCRP (Bcrp1) and P-gp/BCRP inhibitors on the in vivo absorption, distribution, metabolism and excretion of imatinib

Roos L. Oostendorp, Tessa Buckle, Jos H. Beijnen et al. · Investigational New Drugs · 2008 · 135 citations

Pharmacy, Pharmacokinetics, Pharmacology +12

Coadministration of Ritonavir Strongly Enhances the Apparent Oral Bioavailability of Docetaxel in Patients with Solid Tumors

Roos L. Oostendorp, Alwin D. R. Huitema, Hilde Rosing et al. · Clinical Cancer Research · 2009 · 78 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +17

Determination of imatinib mesylate and its main metabolite (CGP74588) in human plasma and murine specimens by ion‐pairing reversed‐phase high‐performance liquid chromatography

Roos L. Oostendorp, Jos H. Beijnen, Jan H.M. Schellens et al. · Biomedical Chromatography · 2007 · 50 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +17

Organic Anion-Transporting Polypeptide 1B1 Mediates Transport of Gimatecan and BNP1350 and Can Be Inhibited by Several Classic ATP-Binding Cassette (ABC) B1 and/or ABCG2 Inhibitors

Roos L. Oostendorp, Evita van de Steeg, Cornelia M.M. van der Kruijssen et al. · Drug Metabolism and Disposition · 2009 · 49 citations

Pharmacy, Pharmacokinetics, Pharmacology +15