Cornelia M.M. van der Kruijssen

Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism

Antonius E. van Herwaarden, Els Wagenaar, Cornelia M.M. van der Kruijssen et al. · Journal of Clinical Investigation · 2007 · 234 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Organic anion transporting polypeptide 1a/1b–knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs

Evita van de Steeg, Els Wagenaar, Cornelia M.M. van der Kruijssen et al. · Journal of Clinical Investigation · 2010 · 227 citations · Full text

Medicine, Biochemistry, Pharmacology +16

Methotrexate Pharmacokinetics in Transgenic Mice with Liver-Specific Expression of Human Organic Anion-Transporting Polypeptide 1B1 (SLCO1B1)

Evita van de Steeg, Cornelia M.M. van der Kruijssen, Els Wagenaar et al. · Drug Metabolism and Disposition · 2008 · 123 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Midazolam Metabolism in Cytochrome P450 3A Knockout Mice Can Be Attributed to Up-Regulated CYP2C Enzymes

Robert A.B. van Waterschoot, Antonius E. van Herwaarden, Jurjen S. Lagas et al. · Molecular Pharmacology · 2007 · 113 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +13

Absence of Both Cytochrome <i>P</i> 450 3A and P-glycoprotein Dramatically Increases Docetaxel Oral Bioavailability and Risk of Intestinal Toxicity

Robert A.B. van Waterschoot, Jurjen S. Lagas, Els Wagenaar et al. · Cancer Research · 2009 · 97 citations

Pharmacy, Pharmacokinetics, Pharmacology +17