Robert A.B. van Waterschoot

Author

Also Known As

R. A. B. van Waterschoot, R. Waterschoot, Robert A. B. van Waterschoot, Robert A.B. Van Waterschoot, Robert A.B. van Waterschoot, Robert AB. van Waterschoot

Publications

1.4K

Citations

H-Index

Concepts

All Affiliations

The Netherlands Cancer Institute Slotervaartziekenhuis Oncode Institute Utrecht University

About

Robert A.B. van Waterschoot is an author at The Netherlands Cancer Institute specializing in medicine, pharmacology, and metabolomics.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	164
2	Natural Sciences	2	2	60
3	Biochemistry	2	2	60
4	Cell Biology	2	2	84
5	Health Sciences	1	1	53

Robert A.B. van Waterschoot

Publications

1.2K

Citations

H-Index

Page 1

	Year	Citations
Knockout of cytochrome P450 3A yields new mouse models for understanding xenobiotic metabolism Antonius E. van Herwaarden, Els Wagenaar, Cornelia M.M. van der Kruijssen, Journal of Clinical Investigation	2007	234
Breast Cancer Resistance Protein and P-glycoprotein Limit Sorafenib Brain Accumulation Jurjen S. Lagas, Robert A.B. van Waterschoot, Rolf W. Sparidans, Molecular Cancer Therapeutics	2010	180
Brain Accumulation of Dasatinib Is Restricted by P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) and Can Be Enhanced by Elacridar Treatment Jurjen S. Lagas, Robert A.B. van Waterschoot, Vicky A.C.J. van Tilburg, Clinical Cancer Research	2009	171
Midazolam Metabolism in Cytochrome P450 3A Knockout Mice Can Be Attributed to Up-Regulated CYP2C Enzymes Robert A.B. van Waterschoot, Antonius E. van Herwaarden, Jurjen S. Lagas, Molecular Pharmacology	2007	110
Absence of Both Cytochrome <i>P</i> 450 3A and P-glycoprotein Dramatically Increases Docetaxel Oral Bioavailability and Risk of Intestinal Toxicity Robert A.B. van Waterschoot, Jurjen S. Lagas, Els Wagenaar, Cancer Research	2009	97
Inhibition and Stimulation of Intestinal and Hepatic CYP3A Activity: Studies in Humanized CYP3A4 Transgenic Mice Using Triazolam Robert A.B. van Waterschoot, Rogier W. Rooswinkel, Rolf W. Sparidans, Drug Metabolism and Disposition	2009	63
P-Glycoprotein Limits Oral Availability, Brain Penetration, and Toxicity of an Anionic Drug, the Antibiotic Salinomycin Jurjen S. Lagas, Rolf W. Sparidans, Robert A.B. van Waterschoot, Antimicrobial Agents and Chemotherapy	2008	62
How important is intestinal cytochrome P450 3A metabolism? Antonius E. van Herwaarden, Robert A.B. van Waterschoot, Alfred H. Schinkel Trends in Pharmacological Sciences Energy MetabolismMedicinePhysiologyMetabolomicsMetabolism	2009	53
Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver Robert A.B. van Waterschoot, Rogier W. Rooswinkel, Els Wagenaar, The FASEB Journal Nuclear Receptors PxrExperimental PharmacologyRedox BiologyToxicological MechanismOxidative Stress	2008	50
Individual and combined roles of CYP3A, P‐glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) in the pharmacokinetics of docetaxel Robert A.B. van Waterschoot, Jurjen S. Lagas, Els Wagenaar, International Journal of Cancer	2010	50

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