Rolf W. Sparidans

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export

Raymond Evers, Marcel de Haas, Rolf W. Sparidans et al. · British Journal of Cancer · 2000 · 227 citations · Full text

Medicine, Biochemistry, Pharmacology +13

Breast Cancer Resistance Protein and P-glycoprotein Limit Sorafenib Brain Accumulation

Jurjen S. Lagas, Robert A.B. van Waterschoot, Rolf W. Sparidans et al. · Molecular Cancer Therapeutics · 2010 · 182 citations

Medicine, Pharmacokinetics, Pharmacology +17

Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease

Pim J. Koelink, Saskia A. Overbeek, Saskia Braber et al. · Gut · 2013 · 167 citations · Full text

Life Sciences, Immunology, Pathobiology +17

Increased oral availability and brain accumulation of the ALK inhibitor crizotinib by coadministration of the P‐glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor elacridar

Seng Chuan Tang, Luan N. Nguyen, Rolf W. Sparidans et al. · International Journal of Cancer · 2013 · 144 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Oral Availability and Brain Penetration of the B-RAF ^V600E Inhibitor Vemurafenib Can Be Enhanced by the P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) Inhibitor Elacridar

Selvi Durmuş, Rolf W. Sparidans, Els Wagenaar et al. · Molecular Pharmaceutics · 2012 · 125 citations

Medicine, Oncology, Pharmacology +16