Alwin D. R. Huitema

Piraña and PCluster: A modeling environment and cluster infrastructure for NONMEM

Ron J. Keizer, Michel van Benten, Jos H. Beijnen et al. · Computer Methods and Programs in Biomedicine · 2010 · 328 citations

Cluster Computing, Massively-parallel Computing, Engineering +14

The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs

Daphne van der Velden, Louisa R. Hoes, Hanneke van der Wijngaart et al. · Nature · 2019 · 252 citations · Full text

Drug Repositioning, Oncology, Preclinical Drug Evaluation +11

Incorporation of concentration data below the limit of quantification in population pharmacokinetic analyses

Ron J. Keizer, Robert S. Jansen, Hilde Rosing et al. · Pharmacology Research & Perspectives · 2015 · 188 citations · Full text

Pharmacokinetics of Miltefosine in Old World Cutaneous Leishmaniasis Patients

Thomas P. C. Dorlo, P. P. A. M. van Thiel, Alwin D. R. Huitema et al. · Antimicrobial Agents and Chemotherapy · 2008 · 163 citations · Full text

Prospective experimental treatment of colorectal cancer patients based on organoid drug responses

Salo Ooft, Fleur Weeber, Luuk J. Schipper et al. · ESMO Open · 2021 · 135 citations · Full text

Oncology, Medicine, Organoid Drug Responses +7