Alexandru D. Buhimschi

Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead

Daniel P. Bondeson, Blake E. Smith, George M. Burslem et al. · Cell chemical biology · 2017 · 867 citations · Full text

Protac Design, Selective Degradation, Biomolecular Engineering +1

Targeting the C481S Ibrutinib-Resistance Mutation in Bruton’s Tyrosine Kinase Using PROTAC-Mediated Degradation

Alexandru D. Buhimschi, Haley A. Armstrong, Momar Toure et al. · Biochemistry · 2018 · 361 citations

Tyrosine Kinase, Immunology, Molecular Biology +19

Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties

Saul Jaime‐Figueroa, Alexandru D. Buhimschi, Momar Toure et al. · Bioorganic & Medicinal Chemistry Letters · 2019 · 87 citations · Full text

Improved Pharmacokinetic Properties, Pharmaceutical Science, Engineering +10

Psoralen Derivatives with Enhanced Potency

Alexandru D. Buhimschi, David M. Gooden, Hongwu Jing et al. · Photochemistry and Photobiology · 2020 · 38 citations · Full text

Medicinal Chemistry, Ultraviolet Radiation, Derivative (Chemistry) +14

<scp>UVA</scp> and <scp>UVB</scp>‐Induced 8‐Methoxypsoralen Photoadducts and a Novel Method for their Detection by Surface‐Enhanced Laser Desorption Ionization Time‐of‐Flight Mass Spectrometry (<scp>SELDI</scp>‐<scp>TOF MS</scp>)

Alexandru D. Buhimschi, Francis P. Gasparro · Photochemistry and Photobiology · 2013 · 10 citations