Momar Toure

The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

George M. Burslem, Blake E. Smith, Ashton C. Lai et al. · Cell chemical biology · 2017 · 643 citations · Full text

Protein Chemistry, Protein Function, Biochemistry +14

Modular PROTAC Design for the Degradation of Oncogenic BCR‐ABL

Ashton C. Lai, Momar Toure, Doris Hellerschmied et al. · Angewandte Chemie International Edition · 2015 · 606 citations · Full text

Targeting the C481S Ibrutinib-Resistance Mutation in Bruton’s Tyrosine Kinase Using PROTAC-Mediated Degradation

Alexandru D. Buhimschi, Haley A. Armstrong, Momar Toure et al. · Biochemistry · 2018 · 361 citations

Tyrosine Kinase, Immunology, Molecular Biology +19

Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation

Philipp Ottis, Momar Toure, Philipp M. Cromm et al. · ACS Chemical Biology · 2017 · 171 citations

Molecular Regulation, Molecular Biology, Ubiquitination Characteristics +20

Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties

Saul Jaime‐Figueroa, Alexandru D. Buhimschi, Momar Toure et al. · Bioorganic & Medicinal Chemistry Letters · 2019 · 87 citations · Full text

Improved Pharmacokinetic Properties, Pharmaceutical Science, Engineering +10