Lydia Kutzler

Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of eIF2B

Connie W. Woo, Lydia Kutzler, Scot R. Kimball et al. · Nature Cell Biology · 2012 · 126 citations · Full text

Inflammation, Toll-like Receptors, Toll-like Receptor Activation +9

Rapid Turnover of the mTOR Complex 1 (mTORC1) Repressor REDD1 and Activation of mTORC1 Signaling following Inhibition of Protein Synthesis

Scot R. Kimball, An Dang, Lydia Kutzler et al. · Journal of Biological Chemistry · 2007 · 102 citations · Full text

Molecular Regulation, Mrna Translation, Molecular Biology +18

Evidence for a role for Sestrin1 in mediating leucine-induced activation of mTORC1 in skeletal muscle

Dandan Xu, Kevin L. Shimkus, Holly A. Lacko et al. · American Journal of Physiology-Endocrinology and Metabolism · 2019 · 72 citations · Full text

Muscle Function, Amino Acids, Cellular Physiology +21

Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming

Raquel Buj, Chi‐Wei Chen, Erika S. Dahl et al. · Cell Reports · 2019 · 63 citations · Full text

P16 Loss, Molecular Biology, Metabolic Remodeling +19

ATF4-Mediated Upregulation of REDD1 and Sestrin2 Suppresses mTORC1 Activity during Prolonged Leucine Deprivation

Dandan Xu, Weiwei Dai, Lydia Kutzler et al. · Journal of Nutrition · 2019 · 54 citations · Full text

Inflammation, Signal Transduction, Molecular Physiology +9