Holly A. Lacko

Evidence for a role for Sestrin1 in mediating leucine-induced activation of mTORC1 in skeletal muscle

Dandan Xu, Kevin L. Shimkus, Holly A. Lacko et al. · American Journal of Physiology-Endocrinology and Metabolism · 2019 · 72 citations · Full text

Muscle Function, Amino Acids, Cellular Physiology +21

Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming

Raquel Buj, Chi‐Wei Chen, Erika S. Dahl et al. · Cell Reports · 2019 · 63 citations · Full text

P16 Loss, Molecular Biology, Metabolic Remodeling +19

ATF4-Mediated Upregulation of REDD1 and Sestrin2 Suppresses mTORC1 Activity during Prolonged Leucine Deprivation

Dandan Xu, Weiwei Dai, Lydia Kutzler et al. · Journal of Nutrition · 2019 · 54 citations · Full text

Inflammation, Signal Transduction, Molecular Physiology +9

Simian virus 40 large T antigen contains two independent activities that cooperate with a ras oncogene to transform rat embryo fibroblasts

Jane F. Cavender, A. R. Conn, Mark J. Epler et al. · Journal of Virology · 1995 · 48 citations · Full text

Amino Acids 176, Large T Antigen, Developmental Biology +13

Adding an Rb-binding site to an N-terminally truncated simian virus 40 T antigen restores growth to high cell density, and the T common region in trans provides anchorage-independent growth and rapid growth in low serum concentrations

Mary J. Tevethia, Holly A. Lacko, Timothy D. Kierstead et al. · Journal of Virology · 1997 · 24 citations · Full text

Viral Replication, Amino Acids, Viral Pathogenesis +19