Chi‐Wei Chen

DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer

Yunxiao Meng, Chi‐Wei Chen, Mingo M. H. Yung et al. · Cancer Letters · 2018 · 77 citations · Full text

Cisplatin Resistance, Duoxa1-mediated Ros Production, Medicine +7

Novel Antitumor Indolizino[6,7-<i>b</i>]indoles with Multiple Modes of Action: DNA Cross-Linking and Topoisomerase I and II Inhibition

Ravi Chaniyara, S. D. Tala, Chi‐Wei Chen et al. · Journal of Medicinal Chemistry · 2013 · 73 citations

Molecular Biology, Compounds 18B, Tumor Biology +21

DHS (trans−4,4′-dihydroxystilbene) suppresses DNA replication and tumor growth by inhibiting RRM2 (ribonucleotide reductase regulatory subunit M2)

Chi‐Wei Chen, Yongming Li, Shuya Hu et al. · Oncogene · 2018 · 63 citations · Full text

Redox Signaling, Nucleic Acid Chemistry, Biochemistry +6

Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming

Raquel Buj, Chi‐Wei Chen, Erika S. Dahl et al. · Cell Reports · 2019 · 63 citations · Full text

P16 Loss, Molecular Biology, Metabolic Remodeling +19

Context-dependent activation of SIRT3 is necessary for anchorage-independent survival and metastasis of ovarian cancer cells

Yeon Kim, Piyushi Gupta Vallur, Victoria Jones et al. · Oncogene · 2019 · 62 citations · Full text

Context-dependent Activation, Anchorage-independent Survival, Medicine +7