Ukhyun Jo

Novel and Highly Potent ATR Inhibitor M4344 Kills Cancer Cells With Replication Stress, and Enhances the Chemotherapeutic Activity of Widely Used DNA Damaging Agents

Ukhyun Jo, Ilya S. Senatorov, Astrid Zimmermann et al. · Molecular Cancer Therapeutics · 2021 · 111 citations · Full text

Medicine, Oncology, Pharmacology +15

Chromatin Remodeling and Immediate Early Gene Activation by SLFN11 in Response to Replication Stress

Junko Murai, Hongliang Zhang, Lőrinc Sándor Pongor et al. · Cell Reports · 2020 · 87 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors

Ukhyun Jo, Yasuhisa Murai, Sirisha Chakka et al. · Proceedings of the National Academy of Sciences · 2021 · 77 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20

Heng Li, Kah Suan Lim, Hyungjin Kim et al. · Molecular Cell · 2016 · 75 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR

Ukhyun Jo, Kyong Hwa Park, Young Mi Whang et al. · Oncotarget · 2014 · 58 citations · Full text

Medicine, Oncology, Pharmacology +17