Junko Murai

Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors

Junko Murai, Shar-yin N. Huang, Benu Brata Das et al. · Cancer Research · 2012 · 2.1K citations · Full text

Stereospecific PARP Trapping by BMN 673 and Comparison with Olaparib and Rucaparib

Junko Murai, Shar-yin N. Huang, Amèlie Renaud et al. · Molecular Cancer Therapeutics · 2013 · 745 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Bioorganic Chemistry +15

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Peter M. Bruno, Yunpeng Liu, Ga Young Park et al. · Nature Medicine · 2017 · 510 citations · Full text

Reductive Stress, Apoptosis, Ribosome Biogenesis Stress +7

Resistance to PARP inhibitors by SLFN11 inactivation can be overcome by ATR inhibition

Junko Murai, Ying Feng, Guoying Karen Yu et al. · Oncotarget · 2016 · 284 citations · Full text

Rationale for Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Combination Therapy with Camptothecins or Temozolomide Based on PARP Trapping versus Catalytic Inhibition

Junko Murai, Yiping Zhang, Joel Morris et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 278 citations · Full text