Peter M. Bruno

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Peter M. Bruno, Yunpeng Liu, Ga Young Park et al. · Nature Medicine · 2017 · 510 citations · Full text

Reductive Stress, Apoptosis, Ribosome Biogenesis Stress +7

The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning

Peter M. Bruno, Mengrou Lu, Kady A. Dennis et al. · Proceedings of the National Academy of Sciences · 2020 · 174 citations · Full text

Immunology, Cell Death, Pathology +24

Defining principles of combination drug mechanisms of action

Justin R. Pritchard, Peter M. Bruno, Luke A. Gilbert et al. · Proceedings of the National Academy of Sciences · 2012 · 172 citations · Full text

A Pt(IV) Pro-drug Preferentially Targets Indoleamine-2,3-dioxygenase, Providing Enhanced Ovarian Cancer Immuno-Chemotherapy

Samuel G. Awuah, Yao‐Rong Zheng, Peter M. Bruno et al. · Journal of the American Chemical Society · 2015 · 161 citations · Full text

Tumor Biology, Cancer Immunosurveillance, Compound 2 +15

Breast Cancer Stem Cell Potent Copper(II)–Non‐Steroidal Anti‐Inflammatory Drug Complexes

Janine N. Boodram, I. J. McGregor, Peter M. Bruno et al. · Angewandte Chemie International Edition · 2016 · 141 citations

Breast Oncology, Effective Copper, Medicine +10