Justin R. Pritchard

Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform

Jeremy M. Rock, Forrest Hopkins, Alejandro Chavez et al. · Nature Microbiology · 2017 · 558 citations · Full text

A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress

Peter M. Bruno, Yunpeng Liu, Ga Young Park et al. · Nature Medicine · 2017 · 510 citations · Full text

Reductive Stress, Apoptosis, Ribosome Biogenesis Stress +7

The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning

Peter M. Bruno, Mengrou Lu, Kady A. Dennis et al. · Proceedings of the National Academy of Sciences · 2020 · 174 citations · Full text

Immunology, Cell Death, Pathology +24

Defining principles of combination drug mechanisms of action

Justin R. Pritchard, Peter M. Bruno, Luke A. Gilbert et al. · Proceedings of the National Academy of Sciences · 2012 · 172 citations · Full text

ARTIST: High-Resolution Genome-Wide Assessment of Fitness Using Transposon-Insertion Sequencing

Justin R. Pritchard, Michael C. Chao, Sören Abel et al. · PLoS Genetics · 2014 · 162 citations · Full text

Microbial Growth, Functional Genomics, Engineering +14