Lukas E. Dow

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

Caroline A. Lindemans, Marco Calafiore, Anna Mertelsmann et al. · Nature · 2015 · 1.1K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Vitamin C selectively kills <i>KRAS</i> and <i>BRAF</i> mutant colorectal cancer cells by targeting GAPDH

Jihye Yun, Edouard Mullarky, Changyuan Lu et al. · Science · 2015 · 910 citations

Medicine, Cancer Biology, Oncology +14

A rectal cancer organoid platform to study individual responses to chemoradiation

Karuna Ganesh, Chao Wu, Kevin P. O’Rourke et al. · Nature Medicine · 2019 · 568 citations · Full text

Medicine, Oncology, Radiation Oncology +14

Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer

Lukas E. Dow, Kevin P. O’Rourke, Janelle Simon et al. · Cell · 2015 · 563 citations · Full text

Medicine, Molecular Biology, Oncology +16

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

Philipp Rathert, Mareike Roth, Tobias Neumann et al. · Nature · 2015 · 522 citations · Full text

Life Sciences, Genetics, Molecular Biology +14