Joan O'Leary Bartus

Modification of the hydroxylactone ring of camptothecin: inhibition of mammalian topoisomerase I and biological activity

Robert Hertzberg, Mary Jo Caranfa, Kenneth G. Holden et al. · Journal of Medicinal Chemistry · 1989 · 411 citations

1,4-Cyclohexanecarboxylates:  Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma

Siegfried B. Christensen, Aimee M. Guider, Cornelia J. Forster et al. · Journal of Medicinal Chemistry · 1998 · 150 citations · Full text

Characterization of cAMP-dependent inhibition of LPS-induced TNFα production by rolipram, a specific phosphodiesterase IV (PDE IV) inhibitor

Uma Prabhakar, David B. Lipshutz, Joan O'Leary Bartus et al. · International Journal of Immunopharmacology · 1994 · 137 citations

Molecular Pharmacology, Signal Transduction, Biochemistry +13

Association of the anti-inflammatory activity of phosphodiesterase 4 (PDE4) inhibitors with either inhibition of PDE4 catalytic activity or competition for [3H]rolipram binding

Mary S. Bamette, Joan O'Leary Bartus, Miriam Burman et al. · Biochemical Pharmacology · 1996 · 106 citations

Inhibitory Activity, Anti-inflammatory, Biochemistry +8

Characterization of Herpes Simplex Viruses Selected in Culture for Resistance to Penciclovir or Acyclovir

Robert T. Sarisky, Matthew R. Quail, Philip E. Clark et al. · Journal of Virology · 2001 · 70 citations · Full text