Miriam Burman

1,4-Cyclohexanecarboxylates:  Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma

Siegfried B. Christensen, Aimee M. Guider, Cornelia J. Forster et al. · Journal of Medicinal Chemistry · 1998 · 150 citations · Full text

Suppression of human inflammatory cell function by subtype‐selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B

Carol D. Manning, Miriam Burman, Siegfried B. Christensen et al. · British Journal of Pharmacology · 1999 · 143 citations · Full text

Inflammation, Anti-inflammatory, Subtype‐selective Pde4 Inhibitors +10

Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast.

Theodore J. Torphy, Jeffrey M. Stadel, Miriam Burman et al. · Journal of Biological Chemistry · 1992 · 139 citations · Full text

Proteinlipid Interaction, Signal Transduction, Biochemistry +14

A low-Km, rolipram-sensitive, cAMP-specific phosphodiesterase from human brain. Cloning and expression of cDNA, biochemical characterization of recombinant protein, and tissue distribution of mRNA.

Megan M. McLaughlin, L B Cieslinski, Miriam Burman et al. · Journal of Biological Chemistry · 1993 · 130 citations · Full text

Mapping the functional domains of human recombinant phosphodiesterase 4A: structural requirements for catalytic activity and rolipram binding.

Susanne Jacobitz, Mark McLaughlin, G P Livi et al. · Molecular Pharmacology · 1996 · 117 citations