L B Cieslinski

Identification, characterization and functional role of phosphodiesterase isozymes in human airway smooth muscle.

Theodore J. Torphy, Bradley J. Undem, L B Cieslinski et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 165 citations

Life Sciences, Biochemistry, Pharmacology +14

Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a Selective Inhibitor of Phosphodiesterase 7: In Vitro Studies in Human Monocytes, Lung Macrophages, and CD8+ T-Lymphocytes

Susan J. Smith, L B Cieslinski, Robert Newton et al. · Molecular Pharmacology · 2004 · 164 citations

Medicine, Medicinal Chemistry, Pharmacology +10

1,4-Cyclohexanecarboxylates:  Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma

Siegfried B. Christensen, Aimee M. Guider, Cornelia J. Forster et al. · Journal of Medicinal Chemistry · 1998 · 150 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Suppression of human inflammatory cell function by subtype‐selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B

Carol D. Manning, Miriam Burman, Siegfried B. Christensen et al. · British Journal of Pharmacology · 1999 · 144 citations · Full text

Medicine, Immunology, Pharmacology +14

Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast.

Theodore J. Torphy, Jeffrey M. Stadel, Miriam Burman et al. · Journal of Biological Chemistry · 1992 · 139 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15