Carol D. Manning

1,4-Cyclohexanecarboxylates:  Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma

Siegfried B. Christensen, Aimee M. Guider, Cornelia J. Forster et al. · Journal of Medicinal Chemistry · 1998 · 150 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Suppression of human inflammatory cell function by subtype‐selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B

Carol D. Manning, Miriam Burman, Siegfried B. Christensen et al. · British Journal of Pharmacology · 1999 · 144 citations · Full text

Medicine, Immunology, Pharmacology +14

Expression and Cellular Localization of the CC Chemokines PARC and ELC in Human Atherosclerotic Plaques

Theresa J. Reape, Kim Rayner, Carol D. Manning et al. · American Journal Of Pathology · 1999 · 120 citations · Full text

Life Sciences, Cardiology, Immunology +16

Salbutamol Up-regulates PDE4 Activity and Induces a Heterologous Desensitization of U937 Cells to Prostaglandin E2

Theodore J. Torphy, Han-liang Zhou, James J. Foley et al. · Journal of Biological Chemistry · 1995 · 93 citations · Full text

Life Sciences, Biochemistry, Pharmacology +9

Prolonged beta adrenoceptor stimulation up-regulates cAMP phosphodiesterase activity in human monocytes by increasing mRNA and protein for phosphodiesterases 4A and 4B.

Carol D. Manning, Megan McLaughlin, G P Livi et al. · Journal of Pharmacology and Experimental Therapeutics · 1996 · 87 citations

Life Sciences, Biochemistry, Pharmacology +11