David B. Lipshutz

Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes

Mimi N. Phan, Holly A. Leddy, Bartholomew J. Votta et al. · Arthritis & Rheumatism · 2009 · 300 citations · Full text

Characterization of cAMP-dependent inhibition of LPS-induced TNFα production by rolipram, a specific phosphodiesterase IV (PDE IV) inhibitor

Uma Prabhakar, David B. Lipshutz, Joan O'Leary Bartus et al. · International Journal of Immunopharmacology · 1994 · 137 citations

Molecular Pharmacology, Signal Transduction, Biochemistry +13

The Identification and Pharmacological Characterization of 6-( <i>tert</i> -Butylsulfonyl)- <i>N</i> -(5-fluoro-1 <i>H</i> -indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase

Pamela A. Haile, Bartholomew J. Votta, Robert W. Marquis et al. · Journal of Medicinal Chemistry · 2016 · 122 citations · Full text

Identification and Cloning of a Connective Tissue Growth Factor-like cDNA from Human Osteoblasts Encoding a Novel Regulator of Osteoblast Functions

Sanjay Kumar, Annalisa T. Hand, Janice R. Connor et al. · Journal of Biological Chemistry · 1999 · 99 citations · Full text

Discovery of a First-in-Class Receptor Interacting Protein 2 (RIP2) Kinase Specific Clinical Candidate, 2-((4-(Benzo[<i>d</i>]thiazol-5-ylamino)-6-(<i>tert</i>-butylsulfonyl)quinazolin-7-yl)oxy)ethyl Dihydrogen Phosphate, for the Treatment of Inflammatory Diseases

Pamela A. Haile, Linda Casillas, Bartholomew J. Votta et al. · Journal of Medicinal Chemistry · 2019 · 65 citations · Full text

Chronic Inflammatory Diseases, Drug Target, Immunology +25