Gerald Schwank

Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients

Gerald Schwank, Bon‐Kyoung Koo, Valentina Sasselli et al. · Cell stem cell · 2013 · 1.4K citations · Full text

Fibrosis, Cystic Fibrosis Patients, Functional Repair +7

Sequential cancer mutations in cultured human intestinal stem cells

Jarno Drost, Richard H. van Jaarsveld, Bas Ponsioen et al. · Nature · 2015 · 1.1K citations

Adult Stem Cell, Colorectal Cancer, Sequential Cancer Mutations +5

Tissue-specific mutation accumulation in human adult stem cells during life

Francis Blokzijl, Joep de Ligt, Myrthe Jager et al. · Nature · 2016 · 960 citations · Full text

Embryonic Stem Cell, Developmental Biology, Medicine +9

Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies

Sandro Nuciforo, Isabel Fofana, Matthias S. Matter et al. · Cell Reports · 2018 · 447 citations · Full text

Treatment of a metabolic liver disease by in vivo genome base editing in adult mice

Lukas Villiger, Hiu Man Grisch‐Chan, Helen Lindsay et al. · Nature Medicine · 2018 · 431 citations

Vivo Genome Base, Genetics, Hepatotoxicity +16