Francis Blokzijl

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

Norman Sachs, Joep de Ligt, Oded Kopper et al. · Cell · 2017 · 1.9K citations · Full text

Breast Oncology, Oncology, Engineering +11

Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

Meritxell Huch, Helmuth Gehart, Ruben van Boxtel et al. · Cell · 2014 · 1.6K citations · Full text

Enormous Replication Potential, Adult Stem Cell, Expanded Cells +28

Tissue-specific mutation accumulation in human adult stem cells during life

Francis Blokzijl, Joep de Ligt, Myrthe Jager et al. · Nature · 2016 · 960 citations · Full text

Embryonic Stem Cell, Developmental Biology, Medicine +9

MutationalPatterns: comprehensive genome-wide analysis of mutational processes

Francis Blokzijl, Roel Janssen, Ruben van Boxtel et al. · Genome Medicine · 2018 · 721 citations · Full text

Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer

Jarno Drost, Ruben van Boxtel, Francis Blokzijl et al. · Science · 2017 · 454 citations · Full text