Lukas Villiger

3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial

Carel W. le Roux, Arne Astrup, Ken Fujioka et al. · The Lancet · 2017 · 813 citations

Obesity, Metabolic Syndrome, Nutrition +8

Treatment of a metabolic liver disease by in vivo genome base editing in adult mice

Lukas Villiger, Hiu Man Grisch‐Chan, Helen Lindsay et al. · Nature Medicine · 2018 · 431 citations

Vivo Genome Base, Genetics, Hepatotoxicity +16

Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases

Matthew T. N. Yarnall, Eleonora Ioannidi, Cian Schmitt-Ulms et al. · Nature Biotechnology · 2022 · 395 citations · Full text

Drag-and-drop Genome Insertion, Genetics, Genetic Engineering +11

In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels

Tanja Rothgangl, Melissa K. Dennis, Paulo J.C. Lin et al. · Nature Biotechnology · 2021 · 352 citations · Full text

Growth of Epithelial Organoids in a Defined Hydrogel

Nicolas Broguière, Luca Isenmann, Christian Hirt et al. · Advanced Materials · 2018 · 273 citations · Full text

Tissue Engineering, Engineering, Cell Adhesion +19