Paulo J.C. Lin

Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses

Mohamad‐Gabriel Alameh, István Tombácz, Emily Bettini et al. · Immunity · 2021 · 659 citations · Full text

Vaccination, Nanomedicine, Cross-protection +11

Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA

Nathan M. Belliveau, Jens Huft, Paulo J.C. Lin et al. · Molecular Therapy — Nucleic Acids · 2012 · 646 citations · Full text

Nanoparticles, Nanotherapeutics, Engineering +18

Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice

Paul F. McKay, Kai Hu, Anna K. Blakney et al. · Nature Communications · 2020 · 460 citations · Full text

Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles

Barbara L. Mui, Ying K. Tam, Muthusamy Jayaraman et al. · Molecular Therapy — Nucleic Acids · 2013 · 459 citations · Full text

Cell-based Drug Delivery, Nanomedicine, Engineering +13

A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice

Dorottya Laczkó, Michael J. Hogan, Sushila A. Toulmin et al. · Immunity · 2020 · 376 citations · Full text

Vaccination, Humoral Immune Responses, Vaccine Development +8