Mohammad R. Masjedizadeh

Characterization of the Metabolic Activation of Hepatitis C Virus Nucleoside Inhibitor β-d-2′-Deoxy-2′-fluoro-2′-C-methylcytidine (PSI-6130) and Identification of a Novel Active 5′-Triphosphate Species

Han Ma, Wen-Rong Jiang, Nicole L. Robledo et al. · Journal of Biological Chemistry · 2007 · 114 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

A phase I trial of PRN1008, a novel reversible covalent inhibitor of Bruton's tyrosine kinase, in healthy volunteers

Patrick F. Smith, Janakan Krishnarajah, Philip A. Nunn et al. · British Journal of Clinical Pharmacology · 2017 · 102 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Discovery of Reversible Covalent Bruton’s Tyrosine Kinase Inhibitors PRN473 and PRN1008 (Rilzabrutinib)

Timothy D. Owens, Ken A. Brameld, Erik Verner et al. · Journal of Medicinal Chemistry · 2022 · 78 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

In silico pharmacogenetics of warfarin metabolism

Yingying Guo, Paul Weller, Erin Farrell et al. · Nature Biotechnology · 2006 · 65 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +11

An integrative genomic analysis identifies <i>Bhmt2</i> as a diet-dependent genetic factor protecting against acetaminophen-induced liver toxicity

Hong-Hsing Liu, Peng Lü, Yingying Guo et al. · Genome Research · 2009 · 46 citations · Full text

Life Sciences, Biochemistry, Genetics +15