Timothy D. Owens - Concepedia

Author

Timothy D. Owens

Principia Biopharma (United States)ORCID

Also Known As

Owens, T.D., T. D. OWENS, T. Owens, T.D. Owens, Timothy D Owens, Timothy D. Owens, Timothy Owens

Publications

2.7K

Citations

H-Index

Concepts

All Affiliations

Principia Biopharma (United States)La Roche College University of California, Berkeley Sanofi (United States)ISCO International (United States)

About

Timothy D. Owens is an author at Principia Biopharma (United States) specializing in medicine, pharmacology, and medicinal chemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	12	1.1K
2	Natural Sciences	10	10	1K
3	Biochemistry	9	9	886
4	Biomolecular Engineering	4	4	375
5	Engineering	1	1	119

Timothy D. Owens

Publications

2.6K

Citations

H-Index

Page 1

	Year	Citations
<i>N-tert</i>-Butanesulfinyl Imines: Versatile Intermediates for the Asymmetric Synthesis of Amines Jonathan A. Ellman, Timothy D. Owens, Tony P. Tang Accounts of Chemical Research	2002	817
Prolonged and tunable residence time using reversible covalent kinase inhibitors J. Michael Bradshaw, Jesse M. McFarland, Ville O. Paavilainen, Nature Chemical Biology Medicinal ChemistryBiochemistryMedicineNatural SciencesTunable Residence Time	2015	422
RN486, a Selective Bruton's Tyrosine Kinase Inhibitor, Abrogates Immune Hypersensitivity Responses and Arthritis in Rodents Daigen Xu, Yong Kim, Jennifer Postelnek, Journal of Pharmacology and Experimental Therapeutics	2012	140
Synthesis, Utility, and Structure of Novel Bis(sulfinyl)imidoamidine Ligands for Asymmetric Lewis Acid Catalysis Timothy D. Owens, Frederick J. Hollander, Allen G. Oliver, Journal of the American Chemical Society EngineeringImidoamidine LigandsNatural SciencesDiversity-oriented SynthesisAltmetric Attention Score	2001	119
New Synthetic Technology for Efficient Construction of α-Hydroxy-β-amino Amides via the Passerini Reaction<sup>1</sup> J. Edward Semple, Timothy D. Owens, Khanh Hung Nguyen, Organic Letters -Alpha-ketoamide Protease InhibitorsOrganic ChemistryChemistryPharmaceutical Chemistryα-Hydroxy-β-amino Amides	2000	115
Preclinical Efficacy and Anti-Inflammatory Mechanisms of Action of the Bruton Tyrosine Kinase Inhibitor Rilzabrutinib for Immune-Mediated Disease Claire L. Langrish, J. Michael Bradshaw, Michelle Francesco, The Journal of Immunology	2021	108
Structure-Based Drug Design of RN486, a Potent and Selective Bruton’s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis Yan Lou, Xiaochun Han, A. Kuglstatter, Journal of Medicinal Chemistry Pharmaceutical ScienceTyrosine KinaseImmunologySelective Btk InhibitorsPharmacotherapy	2014	106
Discovery of the Irreversible Covalent FGFR Inhibitor 8-(3-(4-Acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-one (PRN1371) for the Treatment of Solid Tumors Ken A. Brameld, Timothy D. Owens, Erik Verner, Journal of Medicinal Chemistry Drug TargetSolid TumorsPharmacotherapyFgf/fgfr PathwayPotent Fgfr1-4 Inhibitor	2017	95
The Preparation and Utility of Bis(sulfinyl)imidoamidine Ligands for the Copper-Catalyzed Diels−Alder Reaction Timothy D. Owens, Andrew J. Souers, Jonathan A. Ellman The Journal of Organic Chemistry	2002	86
Co‐inhibition of immunoproteasome subunits LMP2 and LMP7 is required to block autoimmunity Michael Basler, Michelle Lindström, Jacob LaStant, EMBO Reports Molecular ImmunologyAutoimmune DiseaseAutoantibody ProductionImmune RegulationImmunology	2018	70

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