Han Ma

The Novel Nucleoside Analog R1479 (4′-Azidocytidine) Is a Potent Inhibitor of NS5B-dependent RNA Synthesis and Hepatitis C Virus Replication in Cell Culture

Klaus Klumpp, Vincent Lévêque, Sophie Le Pogam et al. · Journal of Biological Chemistry · 2005 · 215 citations · Full text

In vitro selected Con1 subgenomic replicons resistant to 2′-C-Methyl-Cytidine or to R1479 show lack of cross resistance

Sophie Le Pogam, Wen-Rong Jiang, Vincent Lévêque et al. · Virology · 2006 · 128 citations

Cross Resistance, Molecular Research, Con1 Subgenomic Replicons +10

Characterization of the Metabolic Activation of Hepatitis C Virus Nucleoside Inhibitor β-d-2′-Deoxy-2′-fluoro-2′-C-methylcytidine (PSI-6130) and Identification of a Novel Active 5′-Triphosphate Species

Han Ma, Wen-Rong Jiang, Nicole L. Robledo et al. · Journal of Biological Chemistry · 2007 · 112 citations · Full text

Selected Replicon Variants with Low-Level In Vitro Resistance to the Hepatitis C Virus NS5B Polymerase Inhibitor PSI-6130 Lack Cross-Resistance with R1479

Samir Ali, Vincent Lévêque, Sophie Le Pogam et al. · Antimicrobial Agents and Chemotherapy · 2008 · 106 citations · Full text

Viral Hepatitis, Immunology, Antiviral Drug Development +14

Transcriptomic analysis of the woodchuck model of chronic hepatitis B

Simon P. Fletcher, Daniel J. Chin, Yongmei Ji et al. · Hepatology · 2012 · 100 citations · Full text