Yingying Guo

Efavirenz Primary and Secondary Metabolism In Vitro and In Vivo: Identification of Novel Metabolic Pathways and Cytochrome P450 2A6 as the Principal Catalyst of Efavirenz 7-Hydroxylation

Evan T. Ogburn, David Jones, Andrea Renee Masters et al. · Drug Metabolism and Disposition · 2010 · 155 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Organocatalytic asymmetric N-sulfonyl amide C-N bond activation to access axially chiral biaryl amino acids

Guanjie Wang, Qianqian Shi, Wanyao Hu et al. · Nature Communications · 2020 · 119 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +8

Advancing Predictions of Tissue and Intracellular Drug Concentrations Using <i>In Vitro</i>, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

Yingying Guo, Xiaoyan Chu, Neil Parrott et al. · Clinical Pharmacology & Therapeutics · 2018 · 116 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15

A Genetic Analysis of Opioid-induced Hyperalgesia in Mice

De‐Yong Liang, Guochun Liao, Jianmei Wang et al. · Anesthesiology · 2006 · 115 citations · Full text

Medicine, Genetics, Pharmacology +15

Fialuridine Induces Acute Liver Failure in Chimeric TK-NOG Mice: A Model for Detecting Hepatic Drug Toxicity Prior to Human Testing

Dan Xu, T. Nishimura, Sachiko Nishimura et al. · PLoS Medicine · 2014 · 86 citations · Full text

Pharmacy, Pharmacology, Toxicology +17