Yingying Guo

Efavirenz Primary and Secondary Metabolism In Vitro and In Vivo: Identification of Novel Metabolic Pathways and Cytochrome P450 2A6 as the Principal Catalyst of Efavirenz 7-Hydroxylation

Evan T. Ogburn, David Jones, Andrea Renee Masters et al. · Drug Metabolism and Disposition · 2010 · 151 citations · Full text

Organocatalytic asymmetric N-sulfonyl amide C-N bond activation to access axially chiral biaryl amino acids

Guanjie Wang, Qianqian Shi, Wanyao Hu et al. · Nature Communications · 2020 · 116 citations · Full text

Novel Organocatalysts, C-n Bond Activation, Engineering +8

A Genetic Analysis of Opioid-induced Hyperalgesia in Mice

De‐Yong Liang, Guochun Liao, Jianmei Wang et al. · Anesthesiology · 2006 · 115 citations · Full text

Advancing Predictions of Tissue and Intracellular Drug Concentrations Using <i>In Vitro</i>, Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

Yingying Guo, Xiaoyan Chu, Neil Parrott et al. · Clinical Pharmacology & Therapeutics · 2018 · 113 citations · Full text

Engineering, Biomedical Engineering, Pharmacokinetic Modeling Approaches +17

Fialuridine Induces Acute Liver Failure in Chimeric TK-NOG Mice: A Model for Detecting Hepatic Drug Toxicity Prior to Human Testing

Dan Xu, T. Nishimura, Sachiko Nishimura et al. · PLoS Medicine · 2014 · 85 citations · Full text