John E. Monahan

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

Jordi Barretina, Giordano Caponigro, Nicolas Stransky et al. · Nature · 2012 · 8.5K citations

Medicine, Oncology, Pharmacology +15

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

Hui Gao, Joshua M. Korn, Stéphane Ferretti et al. · Nature Medicine · 2015 · 1.4K citations

Medicine, Oncology, Pharmacology +12

An F876L Mutation in Androgen Receptor Confers Genetic and Phenotypic Resistance to MDV3100 (Enzalutamide)

Manav Korpal, Joshua M. Korn, Xueliang Gao et al. · Cancer Discovery · 2013 · 565 citations

Medicine, Oncology, Pharmacology +17

Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

Silvia Buonamici, Juliet Williams, Michael Morrissey et al. · Science Translational Medicine · 2010 · 554 citations

Medicine, Oncology, Pharmacology +16

FGFR Genetic Alterations Predict for Sensitivity to NVP-BGJ398, a Selective Pan-FGFR Inhibitor

Vito Guagnano, Audrey Kauffmann, Simon Wöhrle et al. · Cancer Discovery · 2012 · 364 citations · Full text

Medicine, Molecular Genetics, Oncology +17