Simon Wöhrle

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

William Farnaby, Manfred Koegl, Michael J. Roy et al. · Nature Chemical Biology · 2019 · 553 citations · Full text

Tumor Biology, Medicine, Natural Sciences +10

FGFR Genetic Alterations Predict for Sensitivity to NVP-BGJ398, a Selective Pan-FGFR Inhibitor

Vito Guagnano, Audrey Kauffmann, Simon Wöhrle et al. · Cancer Discovery · 2012 · 352 citations · Full text

A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo

Christiane Kofink, Nicole Trainor, Barbara Mair et al. · Nature Communications · 2022 · 194 citations · Full text

Pharmacological inhibition of fibroblast growth factor (FGF) receptor signaling ameliorates FGF23-mediated hypophosphatemic rickets

Simon Wöhrle, Christine Henninger, Olivier Bonny et al. · Journal of Bone and Mineral Research · 2012 · 146 citations · Full text

Fgfr Inhibitors, Pathology, Pharmacological Inhibition +19

FGF receptors control vitamin D and phosphate homeostasis by mediating renal FGF-23 signaling and regulating FGF-23 expression in bone

Simon Wöhrle, Olivier Bonny, Noémie Beluch et al. · Journal of Bone and Mineral Research · 2011 · 145 citations