J. Mosley

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Laurens Kruidenier, Chun‐wa Chung, Zhongjun Cheng et al. · Nature · 2012 · 958 citations · Full text

Life Sciences, Cell Biology, Immunology +14

RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer

Wei Wang, Jill M. Marinis, Allison M. Beal et al. · Cancer Cell · 2018 · 250 citations · Full text

Life Sciences, Immunology, Oncology +16

The crystal structure of phosphorylase b at 6 Å resolution

L.N. Johnson, Neil B. Madsen, J. Mosley et al. · Journal of Molecular Biology · 1974 · 74 citations

Life Sciences, Biochemistry, Biophysics +14

Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase

Philip A. Harris, Nicolas Faucher, Nicolas George et al. · Journal of Medicinal Chemistry · 2019 · 69 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Second Generation of Hydroxyethylamine BACE-1 Inhibitors: Optimizing Potency and Oral Bioavailability

Nicolas Charrier, Brian Clarke, Leanne Cutler et al. · Journal of Medicinal Chemistry · 2008 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15