Concepedia

Melissa Manis

MM

13

Publications

3.3K

Citations

12

H-Index

2019

Active since

Affiliations

Hope Center for Neurological Disorders(Current)

Washington University in St. Louis

Harvard University

Massachusetts General Hospital

Melissa Manis is an author at Hope Center for Neurological Disorders specializing in medicine, neurodegenerative diseases, and neuroscience.

ORCID

Top concepts

Publications per year

2019–2023

13

Publications

13

The sleep-wake cycle regulates brain interstitial fluid tau in mice and CSF tau in humans

Jerrah K. Holth, Sarah K. Fritschi, Chanung Wang et al. · Science · 2019 · 749 citations · Full text

Microglia-mediated T cell infiltration drives neurodegeneration in tauopathy

Xiaoying Chen, Maria Firulyova, Melissa Manis et al. · Nature · 2023 · 543 citations · Full text

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Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model

Yang Shi, Melissa Manis, Justin M. Long et al. · The Journal of Experimental Medicine · 2019 · 430 citations · Full text

TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis

Francesca Cignarella, Fabia Filipello, Bryan Bollman et al. · Acta Neuropathologica · 2020 · 353 citations · Full text

TREM2 function impedes tau seeding in neuritic plaques

Cheryl E. G. Leyns, Maud Gratuze, Sneha Narasimhan et al. · Nature Neuroscience · 2019 · 335 citations

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