A complement–microglial axis drives synapse loss during virus-induced memory impairment

Michael J. Vasek, Charise Garber, Denise Dorsey, +19

Nature

Complement SystemMedicineImmunologyBrain-immune InteractionNeuroscience +5

A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms

In Young Choi, Laura Piccio, Patra Childress, +11

Cell Reports

NutritionImmunologyFastingMultiple Sclerosis SymptomsImmune Dysregulation +17

TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis

Francesca Cignarella, Fabia Filipello, Bryan Bollman, +17

Acta Neuropathologica

TREM2 regulates microglial cell activation in response to demyelination in vivo

Claudia Cantoni, Bryan Bollman, Danilo Licastro, +10

Acta Neuropathologica

InflammationNeurodegenerative DiseasesMedicineImmunologyBrain-immune Interaction +5

Mir-223 regulates the number and function of myeloid-derived suppressor cells in multiple sclerosis and experimental autoimmune encephalomyelitis

Claudia Cantoni, Francesca Cignarella, Laura Ghezzi, +7

Acta Neuropathologica

Autoimmune DiseaseImmune Cell DevelopmentMedicineImmunologyMyeloid-derived Suppressor Cells +10

Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation

Fabia Filipello, Shih‐Feng You, Farzaneh S. Mirfakhar, +20

Acta Neuropathologica

Apolipoprotein E mediation of neuro-inflammation in a murine model of multiple sclerosis

Soomin Shin, Katharine A. Walz, Angela S. Archambault, +6

Journal of Neuroimmunology

InflammationAutoimmune DiseaseSystemic DiseasesMedicineMurine Model +12

Disruption of the mouse Jhy gene causes abnormal ciliary microtubule patterning and juvenile hydrocephalus

Oliver K. Appelbe, Bryan Bollman, Ali Attarwala, +4

Developmental Biology

Developmental BiologyEpendymaGenetic DisorderDevelopmental GeneticsGenetics +8

T cells producing GM-CSF and IL-13 are enriched in the cerebrospinal fluid of relapsing MS patients

Laura Ghezzi, Claudia Cantoni, Francesca Cignarella, +6

Multiple Sclerosis Journal

Targeting IFN-λ Signaling Promotes Recovery from Central Nervous System Autoimmunity

Sindhu Manivasagam, Jessica Williams, Lauren L. Vollmer, +5

The Journal of Immunology

Adaptive Immune SystemImmunologyImmune RegulationImmunologic MechanismCd4 T Cell Responses +24