Sneha Narasimhan

Amyloid-β plaques enhance Alzheimer's brain tau-seeded pathologies by facilitating neuritic plaque tau aggregation

Zhuohao He, Jing Guo, Jennifer D. McBride et al. · Nature Medicine · 2017 · 632 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Amyloid-β Plaques +8

Unique pathological tau conformers from Alzheimer’s brains transmit tau pathology in nontransgenic mice

Jing Guo, Sneha Narasimhan, Lakshmi Changolkar et al. · The Journal of Experimental Medicine · 2016 · 440 citations · Full text

Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain

Sneha Narasimhan, Jing Guo, Lakshmi Changolkar et al. · Journal of Neuroscience · 2017 · 370 citations · Full text

TREM2 function impedes tau seeding in neuritic plaques

Cheryl E. G. Leyns, Maud Gratuze, Sneha Narasimhan et al. · Nature Neuroscience · 2019 · 335 citations

Signal Transduction, Trem2 Function Impedes, Degenerative Pathology +3

Humanization of the entire murine Mapt gene provides a murine model of pathological human tau propagation

Takashi Saito, Naomi Mihira, Yukio Matsuba et al. · Journal of Biological Chemistry · 2019 · 250 citations · Full text