Young‐Choon Moon

PTC124 targets genetic disorders caused by nonsense mutations

Ellen Welch, Elisabeth R. Barton, Jin Zhuo et al. · Nature · 2007 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +8

Self-renewal as a therapeutic target in human colorectal cancer

Antonija Kreso, Peter van Galen, Nicholas Pedley et al. · Nature Medicine · 2013 · 534 citations

Medicine, Cancer Biology, Oncology +14

<i>SMN2</i> splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

Nikolai A. Naryshkin, Marla Weetall, Amal Dakka et al. · Science · 2014 · 526 citations

Life Sciences, Molecular Biology, Neuroscience +17

Targeting of Hematologic Malignancies with PTC299, A Novel Potent Inhibitor of Dihydroorotate Dehydrogenase with Favorable Pharmaceutical Properties

Liangxian Cao, Marla Weetall, Christopher R. Trotta et al. · Molecular Cancer Therapeutics · 2018 · 85 citations

Medicine, Oncology, Pharmacology +14

Small molecule splicing modifiers with systemic HTT-lowering activity

Anuradha Bhattacharyya, Christopher R. Trotta, Jana Narasimhan et al. · Nature Communications · 2021 · 85 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17