Ellen Welch - Concepedia

Author

Ellen Welch

PTC Therapeutics (United States)

Also Known As

E M Welch, E. M. Welch, E. Welch, E.M. Welch, Ellen M Welch, Ellen M. Welch, Ellen Welch, Welch, Ellen

Publications

Citations

H-Index

Concepts

All Affiliations

PTC Therapeutics (United States)University of Massachusetts Chan Medical School University of Southern California Roche (Switzerland)University of Pennsylvania

About

Ellen Welch is an author at PTC Therapeutics (United States) specializing in medicine, genetics, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	13	2.5K
2	Natural Sciences	3	3	659
3	Health Sciences	2	2	71
4	Engineering	1	1	79
5	Language Studies	1	1	23

Ellen Welch

Publications

3.5K

Citations

H-Index

Page 1

	Year	Citations
PTC124 targets genetic disorders caused by nonsense mutations Ellen Welch, Elisabeth R. Barton, Jin Zhuo, Nature Mendelian DisorderGenetic DisorderGeneticsMolecular GeneticsNonsense Mutations	2007	1.1K
<i>SMN2</i> splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy Nikolai A. Naryshkin, Marla Weetall, Amal Dakka, Science GeneticsMolecular BiologyTherapeuticsSplicing VariantSelective Smn2	2014	517
Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial Eitan Kerem, Michael W. Konstan, K. De Boeck, The Lancet Respiratory Medicine AllergyPlacebo-controlled Phase 3Clinical TrialsNonsense-mutation Cystic FibrosisMedicine	2014	333
PTC124 is an orally bioavailable compound that promotes suppression of the human <i>CFTR</i> -G542X nonsense allele in a CF mouse model Ming Du, Xiaoli Liu, Ellen Welch, Proceedings of the National Academy of Sciences	2008	248
Safety, Tolerability, and Pharmacokinetics of PTC124, a Nonaminoglycoside Nonsense Mutation Suppressor, Following Single‐ and Multiple‐Dose Administration to Healthy Male and Female Adult Volunteers Samit Hirawat, Ellen Welch, Gary Elfring, The Journal of Clinical Pharmacology	2007	238
Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression Bijoyita Roy, Westley J. Friesen, Yuki Tomizawa, Proceedings of the National Academy of Sciences	2016	221
An internal open reading frame triggers nonsense-mediated decay of the yeast SPT10 mRNA Ellen Welch The EMBO Journal Transcriptional RegulationNonsense-mediated DecayNatural SciencesGeneticsYeast Spt10 Mrna	1999	107
Spp1 (osteopontin) promotes TGFβ processing in fibroblasts of dystrophin-deficient muscles through matrix metalloproteinases Irina Kramerova, Chino Kumagai-Cresse, Natalia Ermolova, Human Molecular Genetics	2019	95
Polysome-associated mRNAs are substrates for the nonsense-mediated mRNA decay pathway in Saccharomyces cerevisiae. S Zhang, Ellen Welch, Katherine A. Hogan, PubMed Splice Site SelectionSystems BiologyEngineeringSaccharomyces CerevisiaeProtein Biosynthesis	1997	79
Functional rescue of REP1 following treatment with PTC124 and novel derivative PTC-414 in human choroideremia fibroblasts and the nonsense-mediated zebrafish model Mariya Moosajee, Dhani Tracey‐White, Matthew Smart, Human Molecular Genetics	2016	74

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