Concepedia

Nikolai A. Naryshkin

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Statistics

Publications

22

Citations

2.5K

H-Index

20

Active since

1997

Affiliations

PTC Therapeutics (United States)(Current)

Roche (Switzerland)

University of Southern California

Massachusetts General Hospital

Harvard University

Nikolai A. Naryshkin is an author at PTC Therapeutics (United States) specializing in life sciences, neurodegenerative disorders, and neuroscience.

Publications per year

1997–2023

22

Publications

22

<i>SMN2</i> splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

Nikolai A. Naryshkin, Marla Weetall, Amal Dakka et al. · Science · 2014 · 526 citations

Life Sciences, Molecular Biology, Neuroscience +17

Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( <i>SMN2</i> ) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)

Hasane Ratni, Martin Ebeling, John D. Baird et al. · Journal of Medicinal Chemistry · 2018 · 520 citations · Full text

Medicine, Neurology, Pharmacology +14

Age-dependent SMN expression in disease-relevant tissue and implications for SMA treatment

Daniel M. Ramos, Constantin d’Ydewalle, Vijayalakshmi Gabbeta et al. · Journal of Clinical Investigation · 2019 · 193 citations · Full text

Medicine, Neurology, Neuroscience +17

Structural Organization of the RNA Polymerase-Promoter Open Complex

Nikolai A. Naryshkin, Andrey Revyakin, Young-Gyu Kim et al. · Cell · 2000 · 184 citations

Life Sciences, Genetics, Molecular Biology +14

Risdiplam distributes and increases <scp>SMN</scp> protein in both the central nervous system and peripheral organs

Agnès Poirier, Marla Weetall, Katja Heinig et al. · Pharmacology Research & Perspectives · 2018 · 169 citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

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