Agnès Poirier

Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( <i>SMN2</i> ) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)

Hasane Ratni, Martin Ebeling, John D. Baird et al. · Journal of Medicinal Chemistry · 2018 · 492 citations · Full text

Risdiplam distributes and increases <scp>SMN</scp> protein in both the central nervous system and peripheral organs

Agnès Poirier, Marla Weetall, Katja Heinig et al. · Pharmacology Research & Perspectives · 2018 · 160 citations · Full text

Specific Correction of Alternative Survival Motor Neuron 2 Splicing by Small Molecules: Discovery of a Potential Novel Medicine To Treat Spinal Muscular Atrophy

Hasane Ratni, Gary M. Karp, Marla Weetall et al. · Journal of Medicinal Chemistry · 2016 · 111 citations

Potential Novel Medicine, Genetics, Molecular Biology +16

Design, Data Analysis, and Simulation of in Vitro Drug Transport Kinetic Experiments Using a Mechanistic in Vitro Model

Agnès Poirier, Thierry Lavé, Renée Portmann et al. · Drug Metabolism and Disposition · 2008 · 98 citations

A phase 1 healthy male volunteer single escalating dose study of the pharmacokinetics and pharmacodynamics of risdiplam (RG7916, RO7034067), a <i>SMN2</i> splicing modifier

Stefan Sturm, Andreas Guenther, Birgit Jaber et al. · British Journal of Clinical Pharmacology · 2018 · 98 citations · Full text