Martin Ebeling

<i>SMN2</i> splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

Nikolai A. Naryshkin, Marla Weetall, Amal Dakka et al. · Science · 2014 · 517 citations

Genetics, Molecular Biology, Therapeutics +21

Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( <i>SMN2</i> ) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)

Hasane Ratni, Martin Ebeling, John D. Baird et al. · Journal of Medicinal Chemistry · 2018 · 492 citations · Full text

Trace amine-associated receptors form structurally and functionally distinct subfamilies of novel G protein-coupled receptors

Lothar Lindemann, Martin Ebeling, Nicole A. Kratochwil et al. · Genomics · 2005 · 276 citations

Signal Transduction, Molecular Physiology, Biochemistry +10

Binding to SMN2 pre-mRNA-protein complex elicits specificity for small molecule splicing modifiers

Manaswini Sivaramakrishnan, Kathleen McCarthy, Sébastien Campagne et al. · Nature Communications · 2017 · 219 citations · Full text

The CRTC1-SIK1 Pathway Regulates Entrainment of the Circadian Clock

Aarti Jagannath, Rachel Butler, Sofia I.H. Godinho et al. · Cell · 2013 · 218 citations · Full text