Nature Medicine · 2013 · 534 citations · 35 references
MedicineCancer BiologyOncologyMolecular OncologyTumor MicroenvironmentTumor ProgressionCancer ImmunotherapyCancer ProgressionCancer Stem Cell BiologyCancer Stem CellsColorectal CancerMalignant NeoplasmsColorectal Carcinogenesis PathophysiologySelf-renewal RegulationStemness Signaling PathwaysTherapeutic Target IdentificationTherapeutic Target Validation
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Prospective identification of tumorigenic breast cancer cells
Muhammad Al‐Hajj, Max S. Wicha, Adalberto Benito‐Hernández et al. · Proceedings of the National Academy of Sciences · 2003 · 10.4K citations · Full text
Medicine, Cell Biology, Oncology +11
Identification of human brain tumour initiating cells
Sheila K. Singh, Cynthia Hawkins, Ian D. Clarke et al. · Nature · 2004 · 7.4K citations
Medicine, Cancer Biology, Oncology +11
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature · 2006 · 6.4K citations
Medicine, Cancer Biology, Oncology +16
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
Catherine O′Brien, Aaron Pollett, Steven Gallinger et al. · Nature · 2006 · 4.1K citations
Medicine, Cancer Biology, Oncology +11
Identification and expansion of human colon-cancer-initiating cells
Lucia Ricci‐Vitiani, Dario Lombardi, Emanuela Pilozzi et al. · Nature · 2006 · 4K citations
Medicine, Cancer Biology, Oncology +12