Julie E. Cansfield

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 478 citations · Full text

Medicine, Oncology, Pharmacology +8

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

Paul A. Brough, Wynne Aherne, Xavier Barril et al. · Journal of Medicinal Chemistry · 2007 · 445 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Novel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design

Brian Dymock, Xavier Barril, Paul A. Brough et al. · Journal of Medicinal Chemistry · 2005 · 231 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Inhibition of the heat shock protein 90 molecular chaperone <i>in vitro</i> and <i>in vivo</i> by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues

Swee Y. Sharp, Chrisostomos Prodromou, Kathy Boxall et al. · Molecular Cancer Therapeutics · 2007 · 143 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Structure of the complement C5a receptor bound to the extra-helical antagonist NDT9513727

N.J. Robertson, Mathieu Rappas, A.S. Dore et al. · Nature · 2018 · 140 citations

Life Sciences, Immunology, Molecular Biology +12