Swee Y. Sharp

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 478 citations · Full text

Medicine, Oncology, Pharmacology +8

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer

Paul A. Brough, Wynne Aherne, Xavier Barril et al. · Journal of Medicinal Chemistry · 2007 · 445 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

DT-Diaphorase Expression and Tumor Cell Sensitivity to 17-Allylamino,17-demethoxygeldanamycin, an Inhibitor of Heat Shock Protein 90

LR Kelland, Swee Y. Sharp, Paul Rogers et al. · JNCI Journal of the National Cancer Institute · 1999 · 351 citations · Full text

Medicine, Oncology, Pharmacology +16

Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms

Lisa Wright, Xavier Barril, Brian Dymock et al. · Chemistry & Biology · 2004 · 268 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells

Emma L. Davenport, Hannah E. Moore, Alan Dunlop et al. · Blood · 2007 · 239 citations

Life Sciences, Biochemistry, Molecular Biology +12