Swee Y. Sharp - Concepedia

Author

Swee Y. Sharp

Institute of Cancer Research

Also Known As

S Sharp, S Y Sharp, S. Sharp, S. Y. Sharp, S.Y Sharp, S.Y. Sharp, SWEE Y SHARP, SY Sharp, Sharp, S.Y., Sharp, Swee Y.

162

Publications

5.3K

Citations

H-Index

Concepts

All Affiliations

Institute of Cancer Research Cancer Research UK University of Nottingham Royal Marsden NHS Foundation Trust

About

Swee Y. Sharp is an author at Institute of Cancer Research specializing in medicine, pharmacology, and natural sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	17	1.3K
2	Natural Sciences	10	10	800
3	Cell Biology	9	9	615
4	Biochemistry	8	8	756
5	Engineering	1	1	16

Swee Y. Sharp

Publications

4.5K

Citations

H-Index

Page 1

	Year	Citations
NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis Suzanne A. Eccles, Andy Massey, Florence I. Raynaud, Cancer Research	2008	469
4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential Therapeutic Agents for the Treatment of Cancer Paul A. Brough, Wynne Aherne, Xavier Barril, Journal of Medicinal Chemistry	2007	442
DT-Diaphorase Expression and Tumor Cell Sensitivity to 17-Allylamino,17-demethoxygeldanamycin, an Inhibitor of Heat Shock Protein 90 LR Kelland, Swee Y. Sharp, Paul Rogers, JNCI Journal of the National Cancer Institute	1999	350
Structure-Activity Relationships in Purine-Based Inhibitor Binding to HSP90 Isoforms Lisa Wright, Xavier Barril, Brian Dymock, Chemistry & Biology Hsp90 IsoformsSignal TransductionBiochemistryG Protein-coupled ReceptorMedicine	2004	265
Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells Emma L. Davenport, Hannah E. Moore, Alan Dunlop, Blood	2007	237
The identification, synthesis, protein crystal structure and in vitro biochemical evaluation of a new 3,4-diarylpyrazole class of Hsp90 inhibitors Kwai-Ming J. Cheung, Thomas P. Matthews, Karen James, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryDrug TargetBiochemistryHsp90 InhibitorsNatural Sciences	2005	219
Mini-review: discovery and development of platinum complexes designed to circumvent cisplatin resistance Lloyd R. Kèlland, Swee Y. Sharp, Ciaran F. O’Neill, Journal of Inorganic Biochemistry Inorganic ChemistryChromatinPlatinum ComplexesNatural SciencesCoordination Complex	1999	207
Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-<i>d</i>]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone Paul A. Brough, Xavier Barril, Jenifer Borgognoni, Journal of Medicinal Chemistry	2009	173
MGMT-Independent Temozolomide Resistance in Pediatric Glioblastoma Cells Associated with a PI3-Kinase–Mediated <i>HOX</i>/Stem Cell Gene Signature Nathalie Gaspar, Lynley V. Marshall, Lara Perryman, Cancer Research High-grade GliomasCancer BiologyGliomaTumor BiologyResistance Gene Signature	2010	158
Inhibition of the heat shock protein 90 molecular chaperone <i>in vitro</i> and <i>in vivo</i> by novel, synthetic, potent resorcinylic pyrazole/isoxazole amide analogues Swee Y. Sharp, Chrisostomos Prodromou, Kathy Boxall, Molecular Cancer Therapeutics	2007	142

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