Denise E. Sabatino

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Catherine S. Manno, Glenn F. Pierce, Valder R. Arruda et al. · Nature Medicine · 2006 · 2.1K citations

Inflammation, Aav-factor Ix, Host Response +11

CD8+ T-cell responses to adeno-associated virus capsid in humans

Federico Mingozzi, Marcela V. Maus, Daniel J. Hui et al. · Nature Medicine · 2007 · 716 citations

Cd8+ T-cell Responses, Immunology, Antiviral Response +5

A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells

Giang N. Nguyen, J.K. Everett, Samita Kafle et al. · Nature Biotechnology · 2020 · 428 citations · Full text

Histocompatibility, Hepatology, Aav Gene Therapy +10

Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver

Federico Mingozzi, Nicole C. Hasbrouck, Etiena Basner‐Tschakarjan et al. · Blood · 2007 · 245 citations · Full text

Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing

Xinfu Zhang, Weiyu Zhao, Giang N. Nguyen et al. · Science Advances · 2020 · 172 citations · Full text