Giang N. Nguyen

A long-term study of AAV gene therapy in dogs with hemophilia A identifies clonal expansions of transduced liver cells

Giang N. Nguyen, J.K. Everett, Samita Kafle et al. · Nature Biotechnology · 2020 · 445 citations · Full text

Medicine, Hematology, Molecular Medicine +8

Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing

Xinfu Zhang, Weiyu Zhao, Giang N. Nguyen et al. · Science Advances · 2020 · 180 citations · Full text

Pharmacy, Biotechnology, Pharmaceutics +17

Overexpression of factor VIII after AAV delivery is transiently associated with cellular stress in hemophilia A mice

Amy M. Lange, Ekaterina Altynova, Giang N. Nguyen et al. · Molecular Therapy — Methods & Clinical Development · 2016 · 74 citations · Full text

Life Sciences, Hematology, Molecular Biology +13

Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A

Giang N. Nguyen, Lindsey A. George, Joshua I. Siner et al. · Journal of Thrombosis and Haemostasis · 2016 · 48 citations · Full text

Medicine, Hematology, Molecular Biology +13

Long-Term AAV-Mediated Factor VIII Expression in Nine Hemophilia A Dogs: A 10 Year Follow-up Analysis on Durability, Safety and Vector Integration

Giang N. Nguyen, J.K. Everett, Hayley E. Raymond et al. · Blood · 2019 · 26 citations

Medicine, Hematology, Pathology +14