Concepedia

Joshua Siner

JS

Statistics

Publications

5

Citations

341

H-Index

5

Active since

2010

Affiliations

University of Pennsylvania(Current)

Children's Hospital of Philadelphia

University of Alabama at Birmingham

Joshua Siner is an author at University of Pennsylvania specializing in medicine, immunology, and viral immunity.

Top concepts

Publications per year

2010–2016

5

Publications

5

AAV liver expression of FIX-Padua prevents and eradicates FIX inhibitor without increasing thrombogenicity in hemophilia B dogs and mice

Julie M. Crudele, Jonathan D. Finn, Joshua Siner et al. · Blood · 2015 · 151 citations · Full text

Minimal modification in the factor VIII B-domain sequence ameliorates the murine hemophilia A phenotype

Joshua Siner, Nicholas P. Iacobelli, Denise E. Sabatino et al. · Blood · 2013 · 82 citations · Full text

Novel factor VIII variants with a modified furin cleavage site improve the efficacy of gene therapy for hemophilia A

Giang N. Nguyen, Lindsey A. George, Joshua Siner et al. · Journal of Thrombosis and Haemostasis · 2016 · 48 citations · Full text

Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models

Joshua Siner, Benjamin J. Samelson‐Jones, Julie M. Crudele et al. · JCI Insight · 2016 · 36 citations · Full text

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Safety of Liver Gene Transfer Following Peripheral Intravascular Delivery of Adeno-Associated Virus (AAV)-5 and AAV-6 in a Large Animal Model

Patrícia Favaro, Jonathan D. Finn, Joshua Siner et al. · Human Gene Therapy · 2010 · 24 citations · Full text

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